N-Desethylamiodarone HCl

N-Desethylamiodarone HCl - Names and Identifiers

Name	Desethyl Amiodarone Hydrochloride
Synonyms	AMiodarone EP IMpurity B N-Desethylamiodarone HCl Desethyl Amiodarone Hydrochloride Desethyl Amiodarone Hydrochloride D4 N-Desethylamiodarone (hydrochloride) 2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochlorid 2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochloride (2-butylbenzofuran-3-yl)(4-(2-(ethylaMino)ethoxy)-3,5-diiodophenyl)Methanone hydrochloride
CAS	96027-74-6
EINECS	200-659-6

N-Desethylamiodarone HCl - Physico-chemical Properties

Molecular Formula	C23H26ClI2NO3
Molar Mass	653.71938
Melting Point	176-1780C
Flash Point	9℃
Solubility	DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Light Brown
Storage Condition	-20°C Freezer, Under Inert Atmosphere
Stability	Moisture Sensitive

N-Desethylamiodarone HCl - Risk and Safety

Risk Codes	R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R39/23/24/25 -
Safety Description	S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
HS Code	29329990

N-Desethylamiodarone HCl - Reference Information

biological activity

desetylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is the main active metabolite of Amiodarone. Desetylamiodarone hydrochloride is formed by the CYP3A isoenzyme. Amiodarone is an antiarrhythmic drug used to inhibit ATP-sensitive potassium channels with an IC50 of 19.1 μm.

Last Update：2024-04-09 19:05:16